Uptake of Dicyanogold(I) by H9 Cells
نویسندگان
چکیده
Our analyses of blood and urine samples from patients treated with gold-based antiarthritis drugs have shown that the dicyanogold(I) anion, [Au(CN)2]’, is a common metabolite. Previous work by Graham had suggested that [Au(CN)2]" would form as a result of interaction of any of the goldbased drugs with cyanide and that [Au(CN)2]" would be readily taken up by cells. Our own work with red blood cells indicates that in vitro incubation with [Au(CN)2]" leads to rapid uptake of gold.
منابع مشابه
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ورودعنوان ژورنال:
- Metal-Based Drugs
دوره 1 شماره
صفحات -
تاریخ انتشار 1994